Pesquisa sobre: TREFOIL FACTORS 
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Descritor Inglês:   Trefoil Factors 
Descritor Espanhol:   Factores Trefoil 
Descritor Português:   Fatores Trefoil 
Sinônimos Inglês:   TFF Peptides
Trefoil Factor Family Peptides
Trefoil Factor Family Proteins
Trefoil Peptides
Trefoil Proteins  
Categoria:   D12.644.937
Definição Inglês:   A family of small peptides expressed primarily by MUCOUS MEMBRANE EPITHELIAL CELLS in vertebrates. Their structure is highly conserved and is defined by a three-leaved (trefoil) domain of 42 or 43 amino acids; it includes six cysteines that create the trefoil structure through disulfide bridges. Trefoil peptides may form dimers with each other, or associate with MUCINS and other factors. They are important for maintaining epithelial integrity and for protection from noxious agents. 
Nota Histórica Inglês:   2017 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Número do Registro:   56552 
Identificador Único:   D000071162 

Ocorrência na BVS:
 

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